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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for FOLR3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2352
Official gene symbolFOLR3
Full namefolate receptor 3 (gamma)
Aliases,FR-G,FR-gamma,gamma-hFR,
Gene summaryThis gene encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q13
Gene position71846771 - 71850934  Map Viewer
Gene orientationplus
Gene size4164 bp
Gene sequence
OMIM ID602469