Entrez gene ID | | 2352 |
Official gene symbol | | FOLR3 |
Full name | | folate receptor 3 (gamma) |
Aliases | | ,FR-G,FR-gamma,gamma-hFR, |
Gene summary | | This gene encodes a member of the folate receptor (FOLR) family, members of which have a high affinity for folic acid and for several reduced folic acid derivatives, and mediate delivery of 5-methyltetrahydrofolate to the interior of cells. This gene includes two polymorphic variants; the shorter one has two base deletion in the CDS, resulting in a truncated polypeptide, compared to the longer one. Both protein products are constitutively secreted in hematopoietic tissues and are potential serum marker for certain hematopoietic malignancies. The longer protein has a 71% and 79% sequence homology with the FOLR1 and FOLR2 proteins, respectively. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11q13 |
Gene position | | 71846771 - 71850934 Map Viewer |
Gene orientation | | plus |
Gene size | | 4164 bp |
Gene sequence |
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OMIM ID | | 602469 |