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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for MAFF (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID23764
Official gene symbolMAFF
Full namev-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
Aliases,U-MAF,hMafF,
Gene summaryThe protein encoded by this gene is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 22   Locus: 22q13.1
Gene position38597939 - 38612518  Map Viewer
Gene orientationplus
Gene size14580 bp
Gene sequence
OMIM ID604877