Entrez gene ID | | 247 |
Official gene symbol | | ALOX15B |
Full name | | arachidonate 15-lipoxygenase, type B |
Aliases | | ,15-LOX-2, |
Gene summary | | This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17p13.1 |
Gene position | | 7942358 - 7952452 Map Viewer |
Gene orientation | | plus |
Gene size | | 10095 bp |
Gene sequence |
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OMIM ID | | 603697 |