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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PTF1A (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 256297 Official gene symbol PTF1A Full name pancreas specific transcription factor, 1a Aliases ,PTF1-p48,bHLHa29, Gene summary This gene encodes a protein that is a component of the pancreas transcription factor 1 complex (PTF1) and is known to have a role in mammalian pancreatic development. The protein plays a role in determining whether cells allocated to the pancreatic buds continue towards pancreatic organogenesis or revert back to duodenal fates. The protein is thought to be involved in the maintenance of exocrine pancreas-specific gene expression including elastase 1 and amylase. Mutations in this gene cause cerebellar agenesis and loss of expression is seen in ductal type pancreas cancers. [provided by RefSeq] Location Chromosome: 10   Locus: 10p12.2 Gene position 23481460 - 23483181  Map Viewer Gene orientation plus Gene size 1722 bp Gene sequence >PTF1A:23421460..23423181:Length=1722 ATGGACGCGGTGTTGCTGGAGCACTTCCCCGGGGGCCTAGACGCCTTTCCTTCTTCGTAC TTCGACGAGGACGACTTCTTCACCGACCAGTCTTCACGGGACCCCCTGGAGGACGGCGAT GAGCTGCTGGCGGACGAGCAGGCCGAGGTGGAGTTCCTTAGCCACCAGCTCCACGAGTAC TGCTACCGCGACGGGGCGTGCCTGCTGCTGCAGCCCGCGCCCCCGGCCGCCCCGCTAGCG CTCGCCCCGCCGTCCTCGGGGGGCCTCGGTGAGCCAGACGACGGCGGCGGCGGCGGCTAC TGCTGCGAGACGGGGGCGCCCCCAGGCGGCTTCCCCTACTCGCCCGGCTCGCCGCCCTCG TGCCTGGCCTACCCGTGCGCCGGGGCGGCAGTACTGTCTCCCGGGGCGCGGCTGCGCGGC CTGAGCGGAGCGGCGGCTGCGGCGGCGCGGCGCCGGCGGCGGGTGCGCTCCGAGGCGGAG CTGCAGCAGCTGCGGCAGGCGGCCAACGTGCGCGAGCGGCGGCGCATGCAGTCCATCAAC GACGCCTTCGAGGGGCTGCGCTCGCACATCCCCACGCTGCCCTACGAGAAGCGCCTCTCC AAGGTGGACACGCTGCGCCTGGCCATCGGCTACATCAACTTCCTCAGCGAGCTCGTGCAG GCCGACCTGCCCTTGCGCGGCGGTGGCGCGGGCGGCTGCGGGGGGCCGGGCGGCGGCGGG CGCCTGGGCGGGGACAGCCCGGGCAGCCAGGCCCAGAAGGTCATCATCTGCCATCGGGGC ACCCGTAAGTGCTTCCGCTTCCCAGCTCAGGGAGAAGGGGTCGGGCACTCGAAGGCTCCG GAGGGGCTGGGGGAGCTGACTGCCAAGCAGACAGTCGGACCGACGGATTGTCGGTGGGCA CGGAAAAACTTGAATGCGAGCTCGCGTTTCTCGTTTTTTTTTTTTTTTTTATTTTTCTGC CACGTTGACCGCGGCTCTCAAGGGCGCGCGTCCCCGCCAGACTTGCAGCTCCTCGGATTC CTGGGAGGGGACGGTGGGGACTTGAAGTGTGGAGGAAGAGGGTGGTTCTAGTATAACCGG AGAGCACCCAGGAAAGGGTCCTAAAGGACCTGATGGGACCAATGGGAATGTGGTTGGATA TTCACAGTCTGTTTTCTCTTCTCACCTGTCCAGGGTCCCCCTCCCCCAGCGACCCTGATT ATGGCCTCCCTCCCCTAGCAGGACACTCTCTCTCATGGACTGATGAAAAACAACTCAAGG AACAAAATATTATCCGAACAGCCAAAGTCTGGACCCCAGAGGACCCCAGAAAACTCAACA GCAAATCTTCCTTCAACAACATAGAAAACGAACCACCATTTGAGTTTGTGTCCTGAGAAG TCCCAGACTCGGCTGAAGATCTGATTATGTCTCTGTGCATATTGTACATGTAAATATCTA TAATGTAAATGTAATTTAAGAATCAAATTTTTCGAATGGCAATCAACTGTTTATTATTTA TCTATTTATTATCCTGTTGAGTTGATGAAATAGATGATTTCTTTTTAAATATATAATTTA TATAACTTATCCTGATTTTCTGAAAATATGCAATAGCCTATGATTTTCCTGAACTCTGTG TTGTTGGGAGAACTCTGGCCAGAAAACGTCCTGCTTATTTATTGCCAGATATGGTTTATT TCTAAGCGTTGTCAATAAATGCTATTTACACCTTTTCCTGAA OMIM ID 607194