Entrez gene ID | | 2580 |
Official gene symbol | | GAK |
Full name | | cyclin G associated kinase |
Aliases | | ,FLJ16629,FLJ40395,MGC99654, |
Gene summary | | In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p16 |
Gene position | | 926174 - 843065 Map Viewer |
Gene orientation | | minus |
Gene size | | 83110 bp |
Gene sequence |
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OMIM ID | | 602052 |