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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GCA (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID25801
Official gene symbolGCA
Full namegrancalcin, EF-hand calcium binding protein
Aliases,GCL,
Gene summaryThis gene product, grancalcin, is a calcium-binding protein abundant in neutrophils and macrophages. It belongs to the penta-EF-hand subfamily of proteins which includes sorcin, calpain, and ALG-2. Grancalcin localization is dependent upon calcium and magnesium. In the absence of divalent cation, grancalcin localizes to the cytosolic fraction; with magnesium alone, it partitions with the granule fraction; and in the presence of magnesium and calcium, it associates with both the granule and membrane fractions, suggesting a role for grancalcin in granule-membrane fusion and degranulation. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q24.2
Gene position163200583 - 163219149  Map Viewer
Gene orientationplus
Gene size18567 bp
Gene sequence
OMIM ID607030