Entrez gene ID | | 25998 |
Official gene symbol | | IBTK |
Full name | | inhibitor of Bruton agammaglobulinemia tyrosine kinase |
Aliases | | ,BTKI,KIAA1417,MGC142256,MGC142258,RP1-93K22.1, |
Gene summary | | The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6q14.1 |
Gene position | | 82957448 - 82879956 Map Viewer |
Gene orientation | | minus |
Gene size | | 77493 bp |
Gene sequence |
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OMIM ID | | 606457 |