Entrez gene ID | | 26038 |
Official gene symbol | | CHD5 |
Full name | | chromodomain helicase DNA binding protein 5 |
Aliases | | ,DKFZp434N231,KIAA0444, |
Gene summary | | Changes in gene expression are associated with changes in chromatin structure, which can result from modification of histones by acetylation and methylation. In addition, SWI/SNF proteins can effect chromatin structure and gene expression by causing ATP-dependent disruption of the nucleosome and by enhancing binding of transcription factors. CHD5 belongs to a group of SWI/SNF proteins called CHD proteins, which contain a SWI/SNF-like helicase/ATPase domain, as well as a DNA-binding domain and a chromodomain that directly modifies chromatin structure (Thompson et al., 2003 [PubMed 12592387]).[supplied by OMIM] |
Location | | Chromosome: 1 Locus: 1p36.31 |
Gene position | | 6240194 - 6161847 Map Viewer |
Gene orientation | | minus |
Gene size | | 78348 bp |
Gene sequence |
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OMIM ID | | 610771 |
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