Entrez gene ID | | 26168 |
Official gene symbol | | SENP3 |
Full name | | SUMO1/sentrin/SMT3 specific peptidase 3 |
Aliases | | ,DKFZp586K0919,DKFZp762A152,SMT3IP1,SSP3, |
Gene summary | | The reversible posttranslational modification of proteins by the addition of small ubiquitin-like SUMO proteins (see SUMO1; MIM 601912) is required for numerous biologic processes. SUMO-specific proteases, such as SENP3, are responsible for the initial processing of SUMO precursors to generate a C-terminal diglycine motif required for the conjugation reaction. They also have isopeptidase activity for the removal of SUMO from high molecular mass SUMO conjugates (Di Bacco et al., 2006 [PubMed 16738315]).[supplied by OMIM] |
Location | | Chromosome: 17 Locus: 17p13 |
Gene position | | 7465319 - 7475287 Map Viewer |
Gene orientation | | plus |
Gene size | | 9969 bp |
Gene sequence |
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OMIM ID | | 612844 |