Entrez gene ID | | 261729 |
Official gene symbol | | STEAP2 |
Full name | | six transmembrane epithelial antigen of the prostate 2 |
Aliases | | ,IPCA1,PCANAP1,PUMPCn,STAMP1,STMP, |
Gene summary | | This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 7 Locus: 7q21 |
Gene position | | 89841000 - 89866992 Map Viewer |
Gene orientation | | plus |
Gene size | | 25993 bp |
Gene sequence |
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OMIM ID | | 605094 |
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