Entrez gene ID | | 267012 |
Official gene symbol | | DAOA |
Full name | | D-amino acid oxidase activator |
Aliases | | ,G72,LG72,SG72, |
Gene summary | | This gene encodes a protein that is an activator of the FAD-dependent enzyme D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder, possibly due to decreased levels of D-serine and decreased NMDA receptor functioning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq] |
Location | | Chromosome: 13 Locus: 13q33.2|13q34 |
Gene position | | 106118216 - 106143383 Map Viewer |
Gene orientation | | plus |
Gene size | | 25168 bp |
Gene sequence |
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OMIM ID | | 607408 |
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