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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GFRA1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2674
Official gene symbolGFRA1
Full nameGDNF family receptor alpha 1
Aliases,DKFZp313E1012,DKFZp686J0156,FLJ10561,FLJ31546,GDNFR,GDNFRA,GFR-ALPHA-1,MGC23045,RET1L,RETL1,TRNR1,
Gene summaryGlial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq]
LocationChromosome: 10   Locus: 10q26.11
Gene position118033126 - 117816436  Map Viewer
Gene orientationminus
Gene size216691 bp
Gene sequence
OMIM ID601496