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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DNAJC2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27000
Official gene symbolDNAJC2
Full nameDnaJ (Hsp40) homolog, subfamily C, member 2
Aliases,MPHOSPH11,MPP11,ZRF1,ZUO1,
Gene summaryThis gene is a member of the M-phase phosphoprotein (MPP) family. The gene encodes a phosphoprotein with a J domain and a Myb DNA-binding domain which localizes to both the nucleus and the cytosol. The protein is capable of forming a heterodimeric complex that associates with ribosomes, acting as a molecular chaperone for nascent polypeptide chains as they exit the ribosome. This protein was identified as a leukemia-associated antigen and expression of the gene is upregulated in leukemic blasts. Also, chromosomal aberrations involving this gene are associated with primary head and neck squamous cell tumors. This gene has a pseudogene on chromosome 6. Alternatively spliced variants which encode different protein isoforms have been described. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q22
Gene position102985320 - 102952921  Map Viewer
Gene orientationminus
Gene size32400 bp
Gene sequence
OMIM ID605502