Entrez gene ID | | 27122 |
Official gene symbol | | DKK3 |
Full name | | dickkopf homolog 3 (Xenopus laevis) |
Aliases | | ,REIC,RIG, |
Gene summary | | This gene encodes a protein that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. The expression of this gene is decreased in a variety of cancer cell lines and it may function as a tumor suppressor gene. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.2 |
Gene position | | 12030917 - 11984543 Map Viewer |
Gene orientation | | minus |
Gene size | | 46375 bp |
Gene sequence |
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OMIM ID | | 605416 |