Entrez gene ID | | 27185 |
Official gene symbol | | DISC1 |
Full name | | disrupted in schizophrenia 1 |
Aliases | | ,C1orf136,FLJ13381,FLJ21640,FLJ25311,FLJ41105,KIAA0457,SCZD9, |
Gene summary | | This gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1q42.1 |
Gene position | | 231762561 - 232177018 Map Viewer |
Gene orientation | | plus |
Gene size | | 414458 bp |
Gene sequence |
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OMIM ID | | 605210 |
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