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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for DISC1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27185
Official gene symbolDISC1
Full namedisrupted in schizophrenia 1
Aliases,C1orf136,FLJ13381,FLJ21640,FLJ25311,FLJ41105,KIAA0457,SCZD9,
Gene summaryThis gene encodes a protein with multiple coiled coil motifs which is located in the nucleus, cytoplasm and mitochondria. The protein is involved in neurite outgrowth and cortical development through its interaction with other proteins. This gene is disrupted in a t(1;11)(q42.1;q14.3) translocation which segregates with schizophrenia and related psychiatric disorders in a large Scottish family. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
LocationChromosome: 1   Locus: 1q42.1
Gene position231762561 - 232177018  Map Viewer
Gene orientationplus
Gene size414458 bp
Gene sequence
OMIM ID605210