Entrez gene ID | | 27202 |
Official gene symbol | | C5AR2 |
Full name | | G protein-coupled receptor 77 |
Aliases | | ,C5L2,GPF77,GPR77, |
Gene summary | | The anaphylatoxins C3a (see MIM 120700), C4a (see MIM 120810), and C5a are cationic fragments generated during the complement cascade that participate in host defense. In the case of inappropriate complement activation, anaphylatoxins may be involved in autoimmunity and sepsis. C5L2 is coexpressed with the C5a receptor, C5AR (C5R1; MIM 113995), on polymorphonuclear neutrophils and may modulate C5AR activity (Gerard et al., 2005 [PubMed 16204243]).[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19q13.33 |
Gene position | | 47840371 - 47845272 Map Viewer |
Gene orientation | | plus |
Gene size | | 4902 bp |
Gene sequence |
| |
OMIM ID | | 609949 |
|