Entrez gene ID | | 27235 |
Official gene symbol | | COQ2 |
Full name | | coenzyme Q2 homolog, prenyltransferase (yeast) |
Aliases | | ,CL640,FLJ13014,FLJ26072, |
Gene summary | | This gene encodes an enzyme that functions in the final steps in the biosynthesis of CoQ (ubiquinone), a redox carrier in the mitochondrial respiratory chain and a lipid-soluble antioxidant. This enzyme, which is part of the coenzyme Q10 pathway, catalyzes the prenylation of parahydroxybenzoate with an all-trans polyprenyl group. Mutations in this gene cause coenzyme Q10 deficiency, a mitochondrial encephalomyopathy, and also COQ2 nephropathy, an inherited form of mitochondriopathy with primary renal involvement. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4q21.23 |
Gene position | | 84206067 - 84184977 Map Viewer |
Gene orientation | | minus |
Gene size | | 21091 bp |
Gene sequence |
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OMIM ID | | 609825 |
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