Entrez gene ID | | 27243 |
Official gene symbol | | CHMP2A |
Full name | | chromatin modifying protein 2A |
Aliases | | ,BC-2,BC2,CHMP2,VPS2,VPS2A, |
Gene summary | | CHMP2A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM] |
Location | | Chromosome: 19 Locus: 19q |
Gene position | | 59066486 - 59062933 Map Viewer |
Gene orientation | | minus |
Gene size | | 3554 bp |
Gene sequence |
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OMIM ID | | 610893 |
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