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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ANGPTL3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27329
Official gene symbolANGPTL3
Full nameangiopoietin-like 3
Aliases,ANGPT5,
Gene summaryThe protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen (FBN)-like domain. The FBN-like domain in angiopoietin-like 3 protein was shown to bind alpha-5/beta-3 integrins, and this binding induced endothelial cell adhesion and migration. This protein may also play a role in the regulation of angiogenesis. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p31.1-p22.3
Gene position63063187 - 63071180  Map Viewer
Gene orientationplus
Gene size7994 bp
Gene sequence
OMIM ID604774