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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for STK39 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27347
Official gene symbolSTK39
Full nameserine threonine kinase 39 (STE20/SPS1 homolog, yeast)
Aliases,DCHT,DKFZp686K05124,PASK,SPAK,
Gene summaryThis gene encodes a serine/threonine kinase that is thought to function in the cellular stress response pathway. The kinase is activated in response to hypotonic stress, leading to phosphorylation of several cation-chloride-coupled cotransporters. The catalytically active kinase specifically activates the p38 MAP kinase pathway, and its interaction with p38 decreases upon cellular stress, suggesting that this kinase may serve as an intermediate in the response to cellular stress. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q24.3
Gene position169104105 - 168810530  Map Viewer
Gene orientationminus
Gene size293576 bp
Gene sequence
OMIM ID607648