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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GLI3 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2737
Official gene symbolGLI3
Full nameGLI family zinc finger 3
Aliases,ACLS,GCPS,PAP-A,PAPA,PAPA1,PAPB,PHS,PPDIV,
Gene summaryThis gene encodes a protein which belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis. Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister-Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. [provided by RefSeq]
LocationChromosome: 7   Locus: 7p13
Gene position42276618 - 42000547  Map Viewer
Gene orientationminus
Gene size276072 bp
Gene sequence
OMIM ID165240