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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for PCLO (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID27445
Official gene symbolPCLO
Full namepiccolo (presynaptic cytomatrix protein)
Aliases,ACZ,DKFZp779G1236,
Gene summarySynaptic vesicles dock and fuse in the active zone of the plasma membrane at chemical synapses. The presynaptic cytoskeletal matrix (PCM), which is associated with the active zone and is situated between synaptic vesicles, is thought to be involved in maintaining the neurotransmitter release site in register with the postsynaptic reception apparatus. The cycling of synaptic vesicles is a multistep process involving a number of proteins (see MIM 603215). Among the components of the PCM that orchestrate these events are Bassoon (BSN; MIM 604020), RIM (RBBP8; MIM 604124), Oboe, and Piccolo (PCLO).[supplied by OMIM]
LocationChromosome: 7   Locus: 7q11.23-q21.3
Gene position82792197 - 82383321  Map Viewer
Gene orientationminus
Gene size408877 bp
Gene sequence
OMIM ID604918