Entrez gene ID | | 27445 |
Official gene symbol | | PCLO |
Full name | | piccolo (presynaptic cytomatrix protein) |
Aliases | | ,ACZ,DKFZp779G1236, |
Gene summary | | Synaptic vesicles dock and fuse in the active zone of the plasma membrane at chemical synapses. The presynaptic cytoskeletal matrix (PCM), which is associated with the active zone and is situated between synaptic vesicles, is thought to be involved in maintaining the neurotransmitter release site in register with the postsynaptic reception apparatus. The cycling of synaptic vesicles is a multistep process involving a number of proteins (see MIM 603215). Among the components of the PCM that orchestrate these events are Bassoon (BSN; MIM 604020), RIM (RBBP8; MIM 604124), Oboe, and Piccolo (PCLO).[supplied by OMIM] |
Location | | Chromosome: 7 Locus: 7q11.23-q21.3 |
Gene position | | 82792197 - 82383321 Map Viewer |
Gene orientation | | minus |
Gene size | | 408877 bp |
Gene sequence |
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OMIM ID | | 604918 |
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