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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ANGPT1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID284
Official gene symbolANGPT1
Full nameangiopoietin 1
Aliases,AGP1,AGPT,ANG1,
Gene summaryAngiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme. The protein also contributes to blood vessel maturation and stability, and may be involved in early development of the heart. [provided by RefSeq]
LocationChromosome: 8   Locus: 8q22.3-q23
Gene position108510254 - 108261710  Map Viewer
Gene orientationminus
Gene size248545 bp
Gene sequence
OMIM ID601667