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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GRB2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2885
Official gene symbolGRB2
Full namegrowth factor receptor-bound protein 2
Aliases,ASH,EGFRBP-GRB2,Grb3-3,MST084,MSTP084,NCKAP2,
Gene summaryThe protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q24-q25
Gene position73401790 - 73314157  Map Viewer
Gene orientationminus
Gene size87634 bp
Gene sequence
OMIM ID108355