Entrez gene ID | | 2888 |
Official gene symbol | | GRB14 |
Full name | | growth factor receptor-bound protein 14 |
Aliases | | ,-, |
Gene summary | | The product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date. [provided by RefSeq] |
Location | | Chromosome: 2 Locus: 2q22-q24 |
Gene position | | 165478360 - 165349323 Map Viewer |
Gene orientation | | minus |
Gene size | | 129038 bp |
Gene sequence |
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