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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GRB14 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2888
Official gene symbolGRB14
Full namegrowth factor receptor-bound protein 14
Aliases,-,
Gene summaryThe product of this gene belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules. This gene encodes a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. This protein likely has an inhibitory effect on receptor tyrosine kinase signaling and, in particular, on insulin receptor signaling. This gene may play a role in signaling pathways that regulate growth and metabolism. Transcript variants have been reported for this gene, but their full-length natures have not been determined to date. [provided by RefSeq]
LocationChromosome: 2   Locus: 2q22-q24
Gene position165478360 - 165349323  Map Viewer
Gene orientationminus
Gene size129038 bp
Gene sequence