Entrez gene ID | | 2889 |
Official gene symbol | | RAPGEF1 |
Full name | | Rap guanine nucleotide exchange factor (GEF) 1 |
Aliases | | ,C3G,DKFZp781P1719,GRF2, |
Gene summary | | This gene encodes a human guanine nucleotide exchange factor. It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases. This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq] |
Location | | Chromosome: 9 Locus: 9q34.3 |
Gene position | | 134612925 - 134452157 Map Viewer |
Gene orientation | | minus |
Gene size | | 160769 bp |
Gene sequence |
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OMIM ID | | 600303 |
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