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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GRIA4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2893
Official gene symbolGRIA4
Full nameglutamate receptor, ionotrophic, AMPA 4
Aliases,GLUR4,GLUR4C,GLURD,
Gene summaryGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq]
LocationChromosome: 11   Locus: 11q22
Gene position105480800 - 105852819  Map Viewer
Gene orientationplus
Gene size372020 bp
Gene sequence
OMIM ID138246