Entrez gene ID | | 29088 |
Official gene symbol | | MRPL15 |
Full name | | mitochondrial ribosomal protein L15 |
Aliases | | ,HSPC145,L15mt,MRP-L15,MRP-L7,RPML7, |
Gene summary | | Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the EcoL15 ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 15q. [provided by RefSeq] |
Location | | Chromosome: 8 Locus: 8q11.2-q13 |
Gene position | | 55047781 - 55061074 Map Viewer |
Gene orientation | | plus |
Gene size | | 13294 bp |
Gene sequence |
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OMIM ID | | 611828 |
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