Entrez gene ID | | 2937 |
Official gene symbol | | GSS |
Full name | | glutathione synthetase |
Aliases | | ,GSHS,MGC14098, |
Gene summary | | Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq] |
Location | | Chromosome: 20 Locus: 20q11.2 |
Gene position | | 33543601 - 33516236 Map Viewer |
Gene orientation | | minus |
Gene size | | 27366 bp |
Gene sequence |
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OMIM ID | | 601002 |
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