Database of mammalian genes
Home

Home Search Browse RAGs User guide FAQs Links Questions Contribute

Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GSTM2 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID2946
Official gene symbolGSTM2
Full nameglutathione S-transferase mu 2 (muscle)
Aliases,GST4,GSTM,GSTM2-2,GTHMUS,MGC117303,
Gene summaryCytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. [provided by RefSeq]
LocationChromosome: 1   Locus: 1p13.3
Gene position110210644 - 110226619  Map Viewer
Gene orientationplus
Gene size15976 bp
Gene sequence
OMIM ID138380