Entrez gene ID | | 29775 |
Official gene symbol | | CARD10 |
Full name | | caspase recruitment domain family, member 10 |
Aliases | | ,BIMP1,CARMA3,MGC142219, |
Gene summary | | The caspase recruitment domain (CARD) is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein homophilic interactions. Like several other CARD proteins, CARD10 belongs to the membrane-associated guanylate kinase (MAGUK) family and activates NF-kappa-B (NFKB; see MIM 164011) through BCL10 (MIM 603517) (Wang et al., 2001 [PubMed 11259443]).[supplied by OMIM] |
Location | | Chromosome: 22 Locus: 22q13.1 |
Gene position | | 37915210 - 37886400 Map Viewer |
Gene orientation | | minus |
Gene size | | 28811 bp |
Gene sequence |
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OMIM ID | | 607209 |
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