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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for GZMB (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3002 Official gene symbol GZMB Full name granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) Aliases ,CCPI,CGL-1,CGL1,CSP-B,CSPB,CTLA1,CTSGL1,HLP,SECT, Gene summary Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response. [provided by RefSeq] Location Chromosome: 14   Locus: 14q11.2 Gene position 25103432 - 25100160  Map Viewer Gene orientation minus Gene size 3273 bp Gene sequence >GZMB:complement(6100160..6103432):Length=3273 CCAAGAGCTAAAAGAGAGCAAGGAGGAAACAACAGCAGCTCCAACCAGGGCAGCCTTCCT GAGAAGATGCAACCAATCCTGCTTCTGCTGGCCTTCCTCCTGCTGCCCAGGGCAGATGCA GGTGAGTGACCGTCTCCACCCTCGGGGGCCCAACCCCATCCCACAGGTCTCCTGCCCTTT CTCCACATTCCTGATCCATCTATCTACCAGGAATGTTCTGAACTCCAGCTCCCATTCTAC CAAGACCCCCCAAGTGTGATGCTGGATAAGCTATCAGCAGGAATGGCAGAGCAGCAGGCC ATTCTCAAGAAGAGCCAGTGGGTACTATCCCTTCCCCAGAGCCCACCTTTGTCACCTGGA GAGTAGGACTTTCCTAGAAGTAAATGGCAGAGGATGGGAAACTAGAAAAGAGAAATATTA AATTATTCTAGAGTAGGCCTGGCTTCTGTTTCTGGGATAAGACAGGTGCTTCTCTCACTG TCTACTTAGGAGAGAAACCCAGAGCTCAGCTGACAGCAGAATTGGTACAATCACTGTCCT CAGAACACTGTTAATGTGTTTGCTCAGTCCCATTCTCCAACTCTGCTTTTCTTCCCTGGC CTTTGGTGGCTCCCCTCTTTCCAAGGATGAGGCACTACGGCAGGCCCCAGCTTCCCTGCT TTCTAGAATTCCACCAGCACTGCTCTACCAGCCCTCATCCAGAGGCTAACTGGAGCCAGT CCATCATGCAGCCATGAACATTTACTGGGCACCCACTACATGTCAGGCTCTAGGAAACAG GATATGACAGTATCTAGATCCCTCCACTTACACCCTGGCCATTAGAAAGCAGCACTATCC TAGACACCACAGGACTCATAAGGGTCTTGGAAACTCACCTGAAACAAAGCAAAGTCAGGA GAGGAATGATCAGGAGCCTCTGGGATTTCACTGTCCCTAAGACAGGTATGCTCGCCTTCA ACTACATATGGAAGAAAGATTTACAGACCAAAGTCTGCTGTTCTTCCCTTTTTCAGAGCA GGAAATTGAAGCCCCTTCCTCCAGGCCACTCCCAACTCCAGGCTATCCCAGGCTCCCAAA TGCCCAGGAGTTCTGGAGCCACTAAGCAGGTGCCCACCCAGCAGATTCCATGGGTGCCCA CAAGCAGACAGACTTTTCCTTCAGGGGAGATCATCGGGGGACATGAGGCCAAGCCCCACT CCCGCCCCTACATGGCTTATCTTATGATCTGGGATCAGAAGTCTCTGAAGAGGTGCGGTG GCTTCCTGATACGAGACGACTTCGTGCTGACAGCTGCTCACTGTTGGGGAAGGTGAGGAG CAGAAAACAGCCCACACCCTCCTGGAAACACTCCACAGAGACCCCTGCCTTCTTCCCAAG GAGCTCCCTGGGCTCCTGTGAACACACATGCCAGGAGGTCTCCTTAGAGGGTGAGAAAAG GGCAGTTAAGTTTGTGGAGAGAGGGGAAGGTTGGTTCCAGAGGTGCTGCTGAAGTAAGAA ACAGCAGAGTGACCAAGCCTGCCATATTTAGAACTGGGGGCATACTTTGGCATAGAATAC AAACTGAAGCAATTCCACCTGTGTTTCTAGGGGGAACCGAACCCTGAGAAACCTGGTGCA ATTACCAGAATTCCAATTCCTGGGGACCGACTGTCCCCTTAATTTCCCCTCAGCTGCAGC CCTGCCCCAGCTGTCACCTGCTCTTCACTGTCTCTGGGCTGTATACCCTGTGACTCCACC CCCATCCTCACTCTGCTCTCTGTGCAGCTCCATAAATGTCACCTTGGGGGCCCACAATAT CAAAGAACAGGAGCCGACCCAGCAGTTTATCCCTGTGAAAAGACCCATCCCCCATCCAGC CTATAATCCTAAGAACTTCTCCAACGACATCATGCTACTGCAGGTGAGGCACACTCCTGC CACTCTTGCTCTTCTTGGTCCAGTTGGTTCCACTCCCCCTGGAATGCCGGCCCTTCCCTC CTTTCCATCCTGGCCTCTTGGTTAGTTCCTATGCCTCAGAGGAGAGGGAAGATTGTGCAG CCCCATCACTGTGTCGGGGCCCAGAAGTTCGTTGGCTGACCTGGACTTTCTTGCCTCTTC CCCACCAGCTGGAGAGAAAGGCCAAGCGGACCAGAGCTGTGCAGCCCCTCAGGCTACCTA GCAACAAGGCCCAGGTGAAGCCAGGGCAGACATGCAGTGTGGCCGGCTGGGGGCAGACGG CCCCCCTGGGAAAACACTCACACACACTACAAGAGGTGAAGATGACAGTGCAGGAAGATC GAAAGTGCGAATCTGACTTACGCCATTATTACGACAGTACCATTGAGTTGTGCGTGGGGG ACCCAGAGATTAAAAAGACTTCCTTTAAGGTAAGACTATGCACCTGCCTGGATTGGCTCT TGGGAGAAAGATGTTTGGGGAATATCTGAGACCTGGAGACTCAAGTAGTGGGGGACTCCT TCACCCACTAGACTGTGATATTTCTCTCTGGAAAGAGAAGAGGGGACTAGACTGAGCTGG GGAGAAATTAGGGCCTCTGCAAACTTACCAGGAGGCTTATGGTGGATGGTGCTTCTTTGG AAGGATGAATTTGCAACACTCCACCCACTCCAGGTCACAGATATTAGGAAACTGTGCCCA CTGGGGGTGCAGTAATTATAACCAGGTGTGTCTTCAGAGGCTGGTACCCAACGTGGTTAA TGGGCTGGTCCTCCATGGTGGACATCAGCCCTCCTTGCCCACTTCTGGGTCCTTAAACAG CCAACGGTCCCACATACCTCCGATCTCAGGATCTGGGGGACATGACGGAGGCTGGCCCCT GGGATGAGGTGAAGCAGTAACAATGTCCAGGGCCAGAGCTTGGCAGCTGGGGGCCACCAG CGGCCTGCCCTGCCCTCTGGTCTCCCACATGTAGGCTGTGCAAGTTGGCCTTTTCTAAAA GGGGGCTTGAGATGGAAGAGAGGGCAGGACCCGGAGGAGCATCAGCTCAGTCCTTCCACT CTCTATTCACAGGGGGACTCTGGAGGCCCTCTTGTGTGTAACAAGGTGGCCCAGGGCATT GTCTCCTATGGACGAAACAATGGCATGCCTCCACGAGCCTGCACCAAAGTCTCAAGCTTT GTACACTGGATAAAGAAAACCATGAAACGCTACTAACTACAGGAAGCAAACTAAGCCCCC GCTGTAATGAAACACCTTCTCTGGAGCCAAGTCCAGATTTACACTGGGAGAGGTGCCAGC AACTGAATAAATACCTCTTAGCTGAGTGGAAAA OMIM ID 123910