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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HBG2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3048 Official gene symbol HBG2 Full name hemoglobin, gamma G Aliases ,FLJ76540, Gene summary The gamma globin genes (HBG1 and HBG2) are normally expressed in the fetal liver, spleen and bone marrow. Two gamma chains together with two alpha chains constitute fetal hemoglobin (HbF) which is normally replaced by adult hemoglobin (HbA) at birth. In some beta-thalassemias and related conditions, gamma chain production continues into adulthood. The two types of gamma chains differ at residue 136 where glycine is found in the G-gamma product (HBG2) and alanine is found in the A-gamma product (HBG1). The former is predominant at birth. The order of the genes in the beta-globin cluster is: 5'- epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. [provided by RefSeq] Location Chromosome: 11   Locus: 11p15.5 Gene position 5276011 - 5274421  Map Viewer Gene orientation minus Gene size 1591 bp Gene sequence >HBG2:complement(5214421..5216011):Length=1591 ACACTCGCTTCTGGAACGTCTGAGGTTATCAATAAGCTCCTAGTCCAGACGCCATGGGTC ATTTCACAGAGGAGGACAAGGCTACTATCACAAGCCTGTGGGGCAAGGTGAATGTGGAAG ATGCTGGAGGAGAAACCCTGGGAAGGTAGGCTCTGGTGACCAGGACAAGGGAGGGAAGGA AGGACCCTGTGCCTGGCAAAAGTCCAGGTCGCTTCTCAGGATTTGTGGCACCTTCTGACT GTCAAACTGTTCTTGTCAATCTCACAGGCTCCTGGTTGTCTACCCATGGACCCAGAGGTT CTTTGACAGCTTTGGCAACCTGTCCTCTGCCTCTGCCATCATGGGCAACCCCAAAGTCAA GGCACATGGCAAGAAGGTGCTGACTTCCTTGGGAGATGCCATAAAGCACCTGGATGATCT CAAGGGCACCTTTGCCCAGCTGAGTGAACTGCACTGTGACAAGCTGCATGTGGATCCTGA GAACTTCAAGGTGAGTCCAGGAGATGTTTCAGCACTGTTGCCTTTAGTCTCGAGGCAACT TAGACAACTGAGTATTGATCTGAGCACAGCAGGGTGTGAGCTGTTTGAAGATACTGGGGT TGGGAGTGAAGAAACTGCAGAGGACTAACTGGGCTGAGACCCAGTGGCAATGTTTTAGGG CCTAAGGAGTGCCTCTGAAAATCTAGATGGACAACTTTGACTTTGAGAAAAGAGAGGTGG AAATGAGGAAAATGACTTTTCTTTATTAGATTTCGGTAGAAAGAACTTTCACCTTTCCCC TATTTTTGTTATTCGTTTTAAAACATCTATCTGGAGGCAGGACAAGTATGGTCATTAAAA AGATGCAGGCAGAAGGCATATATTGGCTCAGTCAAAGTGGGGAACTTTGGTGGCCAAACA TACATTGCTAAGGCTATTCCTATATCAGCTGGACACATATAAAATGCTGCTAATGCTTCA TTACAAACTTATATCCTTTAATTCCAGATGGGGGCAAAGTATGTCCAGGGGTGAGGAACA ATTGAAACATTTGGGCTGGAGTAGATTTTGAAAGTCAGCTCTGTGTGTGTGTGTGTGTGT GTGCGCGCGTGTGTTTGTGTGTGTGTGAGAGCGTGTGTTTCTTTTAACGTTTTCAGCCTA CAGCATACAGGGTTCATGGTGGCAAGAAGATAACAAGATTTAAATTATGGCCAGTGACTA GTGCTGCAAGAAGAACAACTACCTGCATTTAATGGGAAAGCAAAATCTCAGGCTTTGAGG GAAGTTAACATAGGCTTGATTCTGGGTGGAAGCTTGGTGTGTAGTTATCTGGAGGCCAGG CTGGAGCTCTCAGCTCACTATGGGTTCATCTTTATTGTCTCCTTTCATCTCAACAGCTCC TGGGAAATGTGCTGGTGACCGTTTTGGCAATCCATTTCGGCAAAGAATTCACCCCTGAGG TGCAGGCTTCCTGGCAGAAGATGGTGACTGGAGTGGCCAGTGCCCTGTCCTCCAGATACC ACTGAGCTCACTGCCCATGATGCAGAGCTTTCAAGGATAGGCTTTATTCTGCAAGCAATC AAATAATAAATCTATTCTGCTAAGAGATCAC OMIM ID 142250