Entrez gene ID | | 3065 |
Official gene symbol | | HDAC1 |
Full name | | histone deacetylase 1 |
Aliases | | ,DKFZp686H12203,GON-10,HD1,RPD3,RPD3L1, |
Gene summary | | Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq] |
Location | | Chromosome: 1 Locus: 1p34 |
Gene position | | 32757708 - 32799224 Map Viewer |
Gene orientation | | plus |
Gene size | | 41517 bp |
Gene sequence |
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OMIM ID | | 601241 |
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