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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HIP1 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3092
Official gene symbolHIP1
Full namehuntingtin interacting protein 1
Aliases,ILWEQ,MGC126506,
Gene summaryThe product of this gene is a membrane-associated protein that colocalizes with huntingtin. This protein has similarities to cytoskeleton proteins and its interaction with huntingtin is thought to play a functional role in the cell filament network. Loss of normal huntingtin-HIP1 interaction in Huntington disease may contribute to a defect in membrane-cytoskeletal integrity in the brain. This gene could help in the understanding of the normal function of huntingtin and also the pathogenesis of Huntington disease. It also has been implicated in the pathogenesis of hematopoietic malignancies. An alternative splice variant of this gene has been described but its full length sequence has not been determined. [provided by RefSeq]
LocationChromosome: 7   Locus: 7q11.23
Gene position75368279 - 75163409  Map Viewer
Gene orientationminus
Gene size204871 bp
Gene sequence
OMIM ID601767