Entrez gene ID | | 3111 |
Official gene symbol | | HLA-DOA |
Full name | | major histocompatibility complex, class II, DO alpha |
Aliases | | ,HLA-DNA,HLA-DZA,HLADZ, |
Gene summary | | HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq] |
Location | | Chromosome: 6 Locus: 6p21.3 |
Gene position | | 32977389 - 32971959 Map Viewer |
Gene orientation | | minus |
Gene size | | 5431 bp |
Gene sequence |
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OMIM ID | | 142930 |
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