Entrez gene ID | | 3131 |
Official gene symbol | | HLF |
Full name | | hepatic leukemia factor |
Aliases | | ,MGC33822, |
Gene summary | | This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q22 |
Gene position | | 53342321 - 53402426 Map Viewer |
Gene orientation | | plus |
Gene size | | 60106 bp |
Gene sequence |
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OMIM ID | | 142385 |
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