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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HMGB2 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3148 Official gene symbol HMGB2 Full name high-mobility group box 2 Aliases ,HMG2, Gene summary This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination. [provided by RefSeq] Location Chromosome: 4   Locus: 4q31 Gene position 174255595 - 174252527  Map Viewer Gene orientation minus Gene size 3069 bp Gene sequence >HMGB2:complement(98800248..98803316):Length=3069 GGGGATGTGGCCCGTGGCCTAGCTCGTCAAGTTGCCGTGGCGCGGAGAACTCTGCAAAAC AAGAGGCTGAGGATTGCGTTAGAGATAAACCAGTTCACGCCGGAGCCCCGTGAGGGAAGC GTCTCCGTTGGGTCCGGCCGCTCTGCGGGACTCTGAGGAAAAGCTCGCACCAGGCAAGAA TACCCTCCAATACCCTCGGGTTCGTGGACCTGCCTTTCCCCATTCCCTCAGAGCCTCTAC TCGGTCTCGGCGCAGTGGCTCTCGGGGTCTGACCCGGCGAGCGGCATTTGGGGTGCGGGC CGGCGAGGGCTGGGTCTGTGGAGGGCCGGCGGGCAGTCGGAGGAGGCGGAAACTGCCCCT GACCGGGCCCGGTTCTGGGAGTTTTCAATGTCGGTCACGAGGTGCTTAGCGGTTAAGTGA GGCTCGCGACGTGGGAGCTGGGGGACATTTCTGTCAGGAAAGGCGTTTTGAGGGCGCTTG CGGAGTCACCGGACTCGGTGAAGGGCGGGCGGCGGCGTCTCGGGCCCCGGGAGCCACTTG CTGGGCTGAGCCGCGGCCGCTCGGGCCGGGAGGAGGAGGAGGAGGAGGGTGTGCGCCGGG GCGCGGGCGGGGGCGCGGGCGGCCGCCCTTGGGAGGACGCCCTCGGGAGGAGGGGGGCGC GGGCAGGGCGGGAGCGGATTTGGGCGGGAAGCGGAGCCCCGCCAGCGCCCGCCCTGGCAG CTGCGGGCTCCGCGCCGACCCTCCGGCTTCCCCTCTCCCCCCTCGGCCCCGTCAGGTGGA CGCGGATCTGTCAACATGGGTAAAGGAGACCCCAACAAGCCGCGGGGCAAAATGTCCTCG TACGCCTTCTTCGTGCAGACCTGCCGGGAAGAGCACAAGAAGAAACACCCGGACTCTTCC GTCAATTTCGCGGAATTCTCCAAGAAGTGTTCGGAGAGATGGAAGGTGAGGCAGGAGAGG GACGGAGCTCAGGGGGTGCAGGTGTGGTTTTCGGCTAGGAGGGCCTTAGGCAGGTAGTAG GCAACTCATGAGCTTCAACTTTGCCACCCCAGTGACTCACCTGAATATCTTAAGAGTTCC AGGCAGACGATTTTAGGTTTTTACTTATATAAGACTTCGAAAGCAAAATGCTGTTAAGGA AAATGTGGTCCTTAAAGATGATCTTGTCGTCTTTGGATGTTTATAGGTAACAATTTTGCT GTATTTTTGGCTCTTATTTTATGTCCACAGACCATGTCTGCAAAGGAGAAGTCGAAGTTT GAAGATATGGCAAAAAGTGACAAAGCTCGCTATGACAGGGAGATGAAAAATTACGTTCCT CCCAAAGGTGATAAGAAGGGGAAGAAAAAGGACCCCAATGCTCCTAAAAGGCCACCGTAA GTTTAAAATAACCCAAATTGCTCCTTGGATTTTTCCTTCAGTTTATTAAACTCTGTTGCT TCCTTTCAGATCTGCCTTCTTCCTGTTTTGCTCTGAACATCGCCCAAAGATCAAAAGTGA ACACCCTGGCCTATCCATTGGGGATACTGCAAAGAAATTGGGTGAAATGTGGTCTGAGCA GTCAGCCAAAGATAAACAACCATATGAACAGAAAGCAGCTAAGCTAAAGGAGAAATATGA AAAGGTACAGTGTCATCTTTTTTAAAGCCGTGGATAAGACTAGGTATAGGTAATAACTGT AGAAAACCTGGGAAATTTAGTTAATCTTGTATTAATGGTTGTCAGCTATGTTTTGAAAAG GCCTAATGAAAATTGTACACTTCAACACAAGGTAATTGAAACCTTCCTTTTGACTGAAAC CAGTGTTTGTAGCACTAGTATATTCCTGCAGACAGACTTGTAGTTACTTGTAGTTATTGT ATAGTCTGTATAGTCTGTTATTTTTTTTTTTAAGCAGAGAGTCAAAGAAATTGTTTTATG TAGATATATATAAAATGTGAAGGTACAGGAGGGACTATGGCACTGTGTGTGATGTAAAAG GGTATTGGTAGTGAAAGTACTGATACTGCTGTATCGCAACCCTTGTCATTTTACGTCATT AACTTGTTAAAGCCTAGTGGGATAAGTGCTCTAAAAACTTAGACTGGTTACCTTTTTAGA CAGTTATTAGGGTTATTGGTCAATCATCTTAGATTGTTTACAACTAAGTGGTTTTTCACA GTTGAGTAATGATACCGGATGCTTTATTTTTTTGACAATATTTCAGGATATTGCTGCATA TCGTGCCAAGGGCAAAAGTGAAGCAGGAAAGAAGGGCCCTGGCAGGCCAACAGGCTCAAA GAAGAAGAACGAACCAGAAGATGAGGAGGAGGAGGAGGAAGAAGAAGATGAAGATGAGGA GGAAGAGGATGAAGATGAAGAATAAATGGCTATCCTTTAATGATGCGTGTGGAATGTGTG TGTGTGCTCAGGCAATTATTTTGCTAAGAATGTGAATTCAAGTGCAGCTCAATACTAGCT TCAGTATAAAAACTGTACAGATTTTTGTATAGCTGATAAGATTCTCTGTAGAGAAAATAC TTTTAAAAAATGCAGGTTGTAGCTTTTTGATGGGCTACTCATACAGTTAGATTTTACAGC TTCTGATGTTGAATGTTCCTAAATATTTAATGGTTTTTTTAATTTCTTGTGTATGGTAGC ACAGCAAACTTGTAGGAATTAGTATCAATAGTAAATTTTGGGTTTTTTAGGATGTTGCAT TTCGTTTTTTTAAAAAAAATTTTGTAATAAAATTATGTATATTATTTCTATTGTCTTTGT CTTAATATGCTAAGTTAATTTTCACTTTAAAAAAGCCATTTGAAGACCAGAGCTATGTTG ATTTTTTTCGGTATTTCTGCCTAGTAGTTCTTAGACACAGTTGACCTAGTAAAATGTTTG AGAATTAAAACCAAACATGCTCATATTTGCAAAATGTTCTTTAAAAGTTACATGTTGAAC TCAGTGAACTTTATAAGAATTTATGCAGTTTTACAGAACGTTAAGTTTTGTACTTGACGT TTCTGTTTATTAGCTAAATTGTTCCTCAGGTGTGTGTATATATATATACATATATATATA TATATATAT OMIM ID 163906