Entrez gene ID | | 3163 |
Official gene symbol | | HMOX2 |
Full name | | heme oxygenase (decycling) 2 |
Aliases | | ,HO-2, |
Gene summary | | Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. Alternative splice variants encoding the same protein have been identified at this locus. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16p13.3 |
Gene position | | 4524719 - 4560348 Map Viewer |
Gene orientation | | plus |
Gene size | | 35630 bp |
Gene sequence |
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OMIM ID | | 141251 |
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