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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for TLX1 (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 3195 Official gene symbol TLX1 Full name T-cell leukemia homeobox 1 Aliases ,HOX11,MGC163402,TCL3, Gene summary This gene encodes a nuclear transcription factor that belongs to the NK-linked or NK-like (NKL) subfamily of homeobox genes. The encoded protein is required for normal development of the spleen during embryogenesis. This protein is also involved in specification of neuronal cell fates. Ectopic expression of this gene due to chromosomal translocations is associated with certain T-cell acute lymphoblastic leukemias. Alternate splicing results in multiple transcript variants. [provided by RefSeq] Location Chromosome: 10   Locus: 10q24 Gene position 102891061 - 102897546  Map Viewer Gene orientation plus Gene size 6486 bp Gene sequence >TLX1:53695525..53702010:Length=6486 TCCCAGAGTCAACAGCGAGCGAGCAGCCGGAGCGGGGAAGCAGAAGCCAGAGAGGGGAAG AATACGGCGCCCCCTCTCTCCCTCCCCTCCCCCTTCTACTTTAGCCTTTCTGCGCACTTC GCTTCCAAGTCTCCGCGCAGCCAGGAGCCGCTGTTGCCTCCCAGCCCCTGCTAGCTGCCC CCCGAGCCGAGCGCAGCGAGCGCCGCCGCCCGGGCCCCCCGGTGGGGCCAGGGCCAGCAT GGAGCACCTGGGTCCGCACCACCTCCACCCGGGTCACGCAGAGCCCATTAGCTTCGGCAT CGACCAGATCCTCAACAGCCCGGACCAGGGTGGCTGCATGGGACCCGCCTCGCGCCTCCA GGACGGAGAATACGGCCTTGGCTGCTTGGTCGGAGGCGCCTACACTTACGGCGGCGGGGG CTCCGCGGCCGCGACGGGGGCTGGAGGAGCGGGGGCCTATGGTACTGGAGGTCCCGGCGG CCCCGGAGGCCCGGCAGGCGGCGGCGGCGCCTGCAGCATGGGTCCTCTGACCGGCTCCTA CAACGTGAACATGGCCTTGGCAGGCGGCCCCGGTCCTGGCGGCGGCGGCGGCAGCAGCGG CGGTGCCGGGGCACTCAGCGCTGCGGGGGTAATCCGGGTGCCGGCACACAGGCCGCTCGC CGGAGCCGTGGCCCACCCCCAGCCCCTGGCCACCGGCTTGCCCACCGTGCCCTCTGTGCC TGCCATGCCGGGCGTCAACAACCTCACTGGCCTCACCTTCCCCTGGATGGAGAGTAACCG CAGATACACAAAGGACAGGTTCACAGGTGAGTCCGGCCCGCGCGCTCCCCGCCTGGCCGC GGCCCGGGCTCCGTGCTACCCCTGCCCCGCCGGGTGGCTCCCCAAAGCCGGTTCTGCGCT CCAGGTCGCCCAGCTCTTCTTGGTGCTTCCCCCAAGTTGAGCCGCCCGCCCGATTCTATA ACGCAGACTCGCCATGCTTGAAGAGTTCTCTCAGCCTGGACCCCTCTCTGTCTCCCGAAG GACCCCTGCTCGGAGGAGCTCTCCCTGGTCCCCTCTCCGGATCCACTAGCCGGGTCAGGC AGAGAGAAGGAGGCCATAGATTCAGGACCACCTTCTGCAGCTACTCTTGGCCTGGGAATC TTAGAGAAAGGGGTGCAACGTGAACAGTTTCTTCCGTCCTGGCTGCTGTTCTAGGACCCA GGAAGCGAGCCCCAGGATCAGACACAAGAAAAGAACAGGTTCCCCCACCTCCAGTCCCCT ACACACATGCACTTCGCGCCCCTAGCTCCGGTGCCCGTGGTGCTGCGGGGCCAGTGGGGG CTCTGAGCCCCGGTAAATCAGCAGAACCAGTGGCCTTTTTTTTTTTTTCCGGAGAGCAGG CTTCATCTGGGAGGATGGCAGCGGGGCTTAGCCGCCCAGGACAGCTAGCTTTTCATTTTC GTTCTCTCCCGGCTGGGTGTCCTACCCCGGGCCCAGCCCTGTTATCTTGGGCACGAACAA TGCACCGGTAGGCTGGTGATCGGTGGCGGGAAGACTACTCCCGGGACATTGGGTACTAAG TGGTGGCCGCTGCCGCCTTCTCTGCTGCCCGCTCCCGCCTTCCTCTGCTGGCCCTGGCTC CCTCTGCTCCCGTTTCCACTCTGGGCACTCAACTCTCCCTCTGGCGTGGATCCCTTCCCC CGTTCTCACTTTCTGCTCCCCTTAGGGTTCCCTGGATCCTAGACCACGATCCTTCCGTCC GGGCTGGGAAGCAGCCACAAATTGAGCCCAGGTTAGCCAGCCGATCTTAGAGAGAGGAGG CAGGAGGCACTGGCTGCTGCTGGCAGAGATGGGGCCTCCTGGGGGTCCCCCGGTTCAAGG GCCCAACAGTGGAAGGGGGGTTTACATAACTACTTGGGAGAAGCTGCTGAGAGCTAGATA CTGGGCCAGGAGATTCCAAAGCACCCCTGGCTTCCTGCTTCTGTTCCAGGCAGCAGCACA GCCAGGGAAACTGCTTCTGCAGCTTCTTACCAGACTCTGGGGCCACGGCAGAAGTGGTGT GGAGGCTGGTGTCCAGAGGAAGAACAGTTGCTTGGGTCTAGGCCTCAGGAAGGGCCCTCC CTAGAGGGGTCCCAGTGCCCCCAACCTAAGTTTTCTCTGGCCTGGGGCAGCAGGGCCTGG TGCCCATCCCATTCCCCACCCAGGCCAGGCCAGTCTTGAAGGGCCCTGCTGGAAACCCAG CCGGGAGTCCACTAATCCTGGGCCTCTGGTGAAAGGTACTCGGTTTAGGGCCTACCGCGG GGCCCTAATACTGTGTCAGGCATGAAGGCGGTTTCAGCGAGTGTATGGCTGTGGCCTTGT TTTGCTCTGTGTCCTGTGTGCTTGTCCCGTGCCTGTGCTTGTCTGGTCCTGTTTGGGTGT ATAGATCTGTGAGTTTGCCCCCGTTGTACGTTGTGTTGGTGTGTGCTGCTGTGGATGGAG GCTCAGGTCGGGTTCCAGAGTCAGGCTCGGCCTCTTACTCTGAGCCTGAAGGCCTGGGGC TGACTGAGGGGAGGGGAGCGTGACCATTAGCTCGCCTTAGACTGCCCCTGGAGGAGAGGC GGCAGGGAGGTGGTTGGGCTCGCGGGAGCCCGGGGCCAGGGAGGCCTCCGTGGTAGCGGC GACGGCGGCGTCGGACTGGCGGGCAGGAGGAGGCCGTTTCCCGCCGTGGGCTTGTCGCTG AGGGCTAACGGGAGGATCTCGGCCCTGCTCGTGGGGGTTCAGCTGCTGCGCTCGCTGACT CGCGGGGTGTTGGGCCTGGGACGCTTCCTGACGCTCTGCTGCTTGCCTCTGCCGTCTGTC TGTCTCCCGCTCCAGTGGCCCTCTCACCCTTCACTGTAACACGCCGTATAGGTCACCCCT ATCAGAACCGGACGCCCCCCAAGAAGAAGAAGCCGCGCACGTCCTTCACACGCCTGCAGA TCTGCGAGCTGGAGAAGCGCTTCCACCGCCAGAAGTACCTGGCCTCGGCCGAGCGCGCCG CCCTGGCCAAGGCGCTCAAAATGACCGATGCGCAGGTCAAAACCTGGTTCCAGAACCGGC GGACAAAGTGGAGGTGAGCAAGCGGGGCGGGCCGGCCGCCCGCGAGCGGCGCGGTCTCAG GCAGCTCTCGGTTCATTGGCCTCTCGTGGGGCGCACATACTTTTTCCGCTCGCGGTTTCT GATCCTTTCGGAGGAGCGAGCTCCCGCTAGGCTTGCGGGGAGCTGGAAGCAACCGAGGCC GATAGCTGGGATGGGGCTGAAGAGCCCTGGCTCTGTTTTACCGGAGGCTTCAGGGCTTTC TGGTTGGCACACTCTCTGCCGGTGTAGACGCGGCAGGTCTATTCCGCCGCTTGGGCAAAC AGGCGGGTTAGTGCACTCCACGCAGTCCAGGCTCCAGGGATCTGTGAGTCCTGGGGAGCT TTTTGTTTGCGCAAACTCTTGCTTATGGAATCCTGCTCTGTCCTGGAGACTGGATGCAGA ACAGCCCGCACCTTGTTGCAGCGCTCCAGCCGGGCTCCCGGCAGAGGGTCTGTGGCCCCA GACCGCGGCCCTGCTGACGGTCTCCTCCCCCAGACACCCGGCCTTTGCGCAGCCGGTCCC TACCCTGGAAGGAGAAAATCAATCCGCGCCGGCTGCGGCGGGGTTTCGCGGGTCCCACTG GAAGGGGAATCAATTAGGAGCAGATGGGTGTGTGTGAGAAAGAGAATTTTCCTTCTCCCA TAGCCACAACTCTAGTTACTACGCAATGGGCTTTTTGTTTTGTTTTGTTTTTTCACATTT ACGCTCACGGACGTGAAGCGTCCCCAACACTCTCGAGCAGCCTCCCTCTCCGCGCGCACT GACGCTTTCTCCGGCTGCACCCTCTGGCACGCTGCACCCTCTGGCACGCTGCACCCTCCC GCACATCTGGCCCTTGCCCGCCGGAGTTTCTCCCCTAGCTCAGGCCCCATGGGGTAGCGC GGGAGAGTCTGGGCGAAGTCGGCGGCGCCGAGACGGGCGGGCCTTGGGGCAGGAGGAAGG AATTGGAGTTTCCTCTTTTTCTGAACGAAGGCGAGGAATCTGCCTGGGATTCCGCCTACG GGGCCACAAAGGAAGCCATGGCCCCACGATTCTACCACAACATTTCTGACGCTGGGAAAG GAGTGGGGGATGCGGCCTCAGACCTTGGAACGCTAAAGAGGGAGCCAGGGCTAGCTCGGG GGTTGGGGGGACTCCGGTTTCCAAGGCCTACTGAGGGCTGCTGGCCTAGGGGAGGAGAGG CAGCCTGGCAGGCCTCCCAGAGAGAGGGGCACAGAGAAAGAAAGAGGCAGGCAAAGAGAG AAACTGAAACACAACCAGTTTCAGAGGTGGAGAGGGATAGGGACCCCGCTCAAGGAAAAA AAAGGAGAAAAACAGGCAGCCTGCAGAAGTCTTATTTATGTATAATAAAGAAAAAGCAAT GGATGACTGAAACCACCATTTTCTTTTCAAACAAATTCCTTTAATTCAGAGAGAACCAAG TGGGTGGGGAGGAGAGAAAACGAGAGATAAGACACAAAGCCTAAAAGAGAAATATTCAGG CCGTTTGAAATGCAGGGGATAAGGGAAAGACGAAAGACGGAAAGATACACAGAGTCAAGA AAAGGCGGCCCAGAGCAGGTCAGCAGCCGCTGCTGGAAGAGGCCCTTGCAGGCTTCGCAT GGCTTCATCGATCGCCTACAAATTGCTTCTGAAGGCCCCAGGGACTCCCATTAGGTCTGT CCACCTTAGAGACAGACGTTTGATCTCAGTTGACAGGGTGGAGGGGCGGCAGTAAATGGA ATAAGTGAGTCATCGCCTCCCTGAACTGCCTCAGAGGAAGCCAGTGGGTCCAGCAGGAGC CCCGGTAGGGCACAGGGCTCCACACAGAAGGCCCAAGTCCTAGAAGACATTCGCAGAGAG AGGGAGGAAAGAGACGTCCCGCAGAGCAGATCGTACCCGCTGGTCCTTGCCTCTCTGCCC TGGACTTGTGGGTAGGGTGAGGGCCCTCTGGCTTGGAATGGCACCTGGTCTCCCTCAGGG CCGGGGAGGGGGAGGCGAGATGCCATCCTACCCCGGCTGCCCCTTGTGAGGCCTCCGGGG TGTGGGCGCTGCGCGTGGATGCGAGTCCCAGCTGTTTGGGCCTCGCAGACTTTCCCATCG CTCCTCCTCTGGGATACCTTGGCTCCATCCGCTTTGGGGTTTCCAGTCTTTGTTGGAGTC AGGACTCTCAAAAGAAGGGAACGCGTTATAGGGGCCCAAACTGGATTTGGGGACTGCAAA GGCGAGCAGCGCTCGTTCAGTTTATCTCCTGGGAACGCACCAGGAGTTGGGCACACGCGG GAGCTGGGTCGGTGCTCCTGGCAGGTAACGGCTTGTTCCCGGTGCAGACGGCAGACTGCG GAGGAACGGGAGGCCGAGAGGCAGCAAGCGAACCGCATCCTCCTGCAGTTGCAGCAGGAG GCCTTCCAGAAGAGCCTGGCACAGCCGCTGCCCGCTGACCCTCTGTGCGTGCACAACTCG TCGCTCTTCGCCCTGCAGAATCTGCAGCCGTGGTCTGACGACTCGACCAAAATCACTAGC GTCACGTCGGTGGCGTCGGCCTGCGAGTGAGCCTGCCCATTCTGCCCTGTGGGACCCCAG GCCCACTCAGGGGTCACTGAGGCCTGAGACCCAGGACTCCTCCCCACCCTCCTGGCCTCA GACTGCACCCAGGAGGGGAACACTGCCCTCGCACGGCCCCGAAGGGCCCCCACATTTGTG CCGACACTGTTCTCCCTTCGGTGGAAGAGCTCAAGGGACAAGGACACGCGCCCCCCTCCC AGAGGCGTCCCGCACCTGTCTGAACTGTTAAGAAATCTGTTTTTGTTTATTTCATTTTAT TTTAATTTTTAACGTGGGATTCAGAGAAAGGCAAGGGAGGTAAGGGAGGAGGAGCTTCTG GGGTCCCCAGGGCTGTCATCTGAATTTGCCCTGGGAAACCCCTTCTCTGTGACCCACTTC TCATCACACACATGGAAACCCATAGGCCCACACACAGGTGGTGTCACTGTCCCTCCTGGT GTCACCCCAGAGCCACACATGGGCATCTATGGGAGAGTGTCAACCAGACAGAGGGTCACA GTGTTTACACTTTGGACCTTACGATCAGGCACAGGTCAGGGGTGACACAGACTCATCCTG AACAGCATGGCACTCCCTCCAGCACAAACACAAGGTCATGGCCACACTGTGACACACTAC ACCACACACAACAGCCAACAGCTACAACAGCCTCACTTGGTCTGCCAGGCCCCCACCACA CATCCCAGCCCAATCCAGGTACGCACAGACAGGTTTTCACATAAATGCAGCCCATTTCTC CAGAACCCATTTGAGGGGTGGGGGGGTGTTAATTTATGCACTTATAAGGTGTTTTCTGTG TAACCATTTTATAAAGTGCTTGTGTAATTTATGTGAAAAAAATAAATAAAAGCCTCCGGA TCCGGA OMIM ID 186770