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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ACACB (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID32
Official gene symbolACACB
Full nameacetyl-CoA carboxylase beta
Aliases,ACC2,ACCB,HACC275,
Gene summary Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. ACC-beta is thought to control fatty acid oxidation by means of the ability of malonyl-CoA to inhibit carnitine-palmitoyl-CoA transferase I, the rate-limiting step in fatty acid uptake and oxidation by mitochondria. ACC-beta may be involved in the regulation of fatty acid oxidation, rather than fatty acid biosynthesis. There is evidence for the presence of two ACC-beta isoforms. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24.11
Gene position109577202 - 109706031  Map Viewer
Gene orientationplus
Gene size128830 bp
Gene sequence
OMIM ID601557