Entrez gene ID | | 3215 |
Official gene symbol | | HOXB5 |
Full name | | homeobox B5 |
Aliases | | ,HHO.C10,HOX2,HOX2A,HU-1,Hox2.1, |
Gene summary | | This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue. [provided by RefSeq] |
Location | | Chromosome: 17 Locus: 17q21.3 |
Gene position | | 46671103 - 46668619 Map Viewer |
Gene orientation | | minus |
Gene size | | 2485 bp |
Gene sequence |
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OMIM ID | | 142960 |