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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HOXB8 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3218
Official gene symbolHOXB8
Full namehomeobox B8
Aliases,HOX2,HOX2D,Hox-2.4,
Gene summaryThis gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with colorectal cancer. Mice that have had the murine ortholog of this gene knocked out exhibit an excessive pathologic grooming behavior. This behavior is similar to the behavior of humans suffering from the obsessive-compulsive spectrum disorder trichotillomania. [provided by RefSeq]
LocationChromosome: 17   Locus: 17q21.3
Gene position46692301 - 46689708  Map Viewer
Gene orientationminus
Gene size2594 bp
Gene sequence
OMIM ID142963