Entrez gene ID | | 323 |
Official gene symbol | | APBB2 |
Full name | | amyloid beta (A4) precursor protein-binding, family B, member 2 |
Aliases | | ,DKFZp434E033,FE65L,FE65L1,MGC35575, |
Gene summary | | The protein encoded by this gene interacts with the cytoplasmic domains of amyloid beta (A4) precursor protein and amyloid beta (A4) precursor-like protein 2. This protein contains two phosphotyrosine binding (PTB) domains, which are thought to function in signal transduction. Polymorphisms in this gene have been associated with Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq] |
Location | | Chromosome: 4 Locus: 4p14-p13 |
Gene position | | 41216635 - 40812044 Map Viewer |
Gene orientation | | minus |
Gene size | | 404592 bp |
Gene sequence |
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OMIM ID | | 602710 |