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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for HPD (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3242
Official gene symbolHPD
Full name4-hydroxyphenylpyruvate dioxygenase
Aliases,4-HPPD,4HPPD,GLOD3,HPPDASE,PPD,
Gene summaryThe protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
LocationChromosome: 12   Locus: 12q24-qter
Gene position122326517 - 122277433  Map Viewer
Gene orientationminus
Gene size49085 bp
Gene sequence
OMIM ID609695