Entrez gene ID | | 331 |
Official gene symbol | | XIAP |
Full name | | X-linked inhibitor of apoptosis |
Aliases | | ,API3,BIRC4,ILP1,MIHA,XLP2, |
Gene summary | | The protein encoded by this gene is a member of a family of proteins which inhibit apoptosis through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2. This protein inhibits apoptosis induced by menadione, a potent inducer of free radicals, and ICE. It also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. [provided by RefSeq] |
Location | | Chromosome: X Locus: Xq25 |
Gene position | | 122993662 - 123047829 Map Viewer |
Gene orientation | | plus |
Gene size | | 53775 bp |
Gene sequence |
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OMIM ID | | 300079 |