Entrez gene ID | | 338323 |
Official gene symbol | | NLRP14 |
Full name | | NLR family, pyrin domain containing 14 |
Aliases | | ,CLR11.2,GC-LRR,NALP14,NOD5,PAN8, |
Gene summary | | The protein encoded by this gene belongs to the NALP protein family. Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain (NAD), a C-terminal leucine-rich repeat (LRR) region, and an N-terminal pyrin domain (PYD). This protein may play a regulatory role in the innate immune system as similar family members belong to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. [provided by RefSeq] |
Location | | Chromosome: 11 Locus: 11p15.4 |
Gene position | | 7041700 - 7092757 Map Viewer |
Gene orientation | | plus |
Gene size | | 51058 bp |
Gene sequence |
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OMIM ID | | 609665 |
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