Entrez gene ID | | 3386 |
Official gene symbol | | ICAM4 |
Full name | | intercellular adhesion molecule 4 (Landsteiner-Wiener blood group) |
Aliases | | ,CD242,LW, |
Gene summary | | This gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq] |
Location | | Chromosome: 19 Locus: 19p13.2-cen |
Gene position | | 10397650 - 10399198 Map Viewer |
Gene orientation | | plus |
Gene size | | 1549 bp |
Gene sequence |
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OMIM ID | | 111250 |