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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for ICAM4 (Homo sapiens)
(Information is obtained from NCBI Gene database)
Entrez gene ID3386
Official gene symbolICAM4
Full nameintercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
Aliases,CD242,LW,
Gene summaryThis gene encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]
LocationChromosome: 19   Locus: 19p13.2-cen
Gene position10397650 - 10399198  Map Viewer
Gene orientationplus
Gene size1549 bp
Gene sequence
OMIM ID111250