Entrez gene ID | | 3394 |
Official gene symbol | | IRF8 |
Full name | | interferon regulatory factor 8 |
Aliases | | ,H-ICSBP,ICSBP,ICSBP1,IRF-8, |
Gene summary | | Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection. [provided by RefSeq] |
Location | | Chromosome: 16 Locus: 16q24.1 |
Gene position | | 85932774 - 85956212 Map Viewer |
Gene orientation | | plus |
Gene size | | 23439 bp |
Gene sequence |
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OMIM ID | | 601565 |