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Gene Protein Transcript Promoter Expression GO/PPI PubMed Cross reference

Gene information for IRGM (Homo sapiens) (Information is obtained from NCBI Gene database)

Entrez gene ID 345611 Official gene symbol IRGM Full name immunity-related GTPase family, M Aliases ,IFI1,IRGM1,LRG-47,LRG47,MGC149263,MGC149264, Gene summary This gene encodes a member of the p47 immunity-related GTPase family. The encoded protein may play a role in the innate immune response by regulating autophagy formation in response to intracellular pathogens. Polymorphisms that affect the normal expression of this gene are associated with a susceptibility to Crohn's disease and tuberculosis. Location Chromosome: 5   Locus: 5q33.1 Gene position 150226085 - 150228231  Map Viewer Gene orientation plus Gene size 2147 bp Gene sequence >IRGM:11389012..11391158:Length=2147 TAACCTGCTCAGGTCCCCTTCCATGCTGTGGAAGCTTTGTTTTTTTGCACTTTGCAGTAA ATCTTGCTGCTGCTCATTCTTTGGGTCCACACTGCCTTTATGAGCTGTAACACTCACCGT GAAGGTCTGCAGCATCACTCCTGAAACCTGTGAAACAACGAACCCCCCGGGGAGAAACGA ACAACTCCAGACTCGCCGCCTGAAGAGCTGTAACTCTCACTTCGAAGGTCTGCAGCTTCG CTCCTGAGTCAGTGAAACCACGAACCCACCGGAAGGAAGAAACTCTGAACACATCCAAAC ATCAGAAGGAACAAACTCCGGACACGCAGCCTTTAAGAATTGTAACACTCACCGCGAGGG TCCGTGGCTTCATTCTTGAAGTCAGTGAGACGAAGAACCCACCAATTCCGGTAGGAGTAG GAAATCACATCACCTTCTTTTAATCAGTCTCAAATACCTGGCCCCTTGTGGAACCTGCAA GAGCCAGGTTTGGCGAATGCAATGATAAGCAATTGTCTAATCACTGCCTTGAAAAAGAGC AGAGCATTTGAGTATGCTGTCTCCTCCTCTCCCTCACTTCAGTTGGGCCCAACATGACAG TCTTAATGGAAGCTCGGGGGTCAAAGGCTGGTGGCTTACTTCACGTATATTGCAGCATTT CAGTACTGCTCTGCACGTGTGCTCCCCCGCCTGATGAGGTAAGTGTTAAACAGGGATGAT CACAGCTTCAAGTAAGCAATGGGAATTGGATGTTTTATGTCCTCTGGCGCCATCTTCAGC AGAGAAATATATAGGTCACTTTTACTTGTCTGGTTTTGGTCTTGAAATATGTACTGAAAC TTGTGAAGGAGCAGACCTATATTAGGATAGAGTAAAAGAGGGAAAGACAAAAACCTCTTG GGCTTTTCAGGAGACTTGGTTCATTCTCTGCTTTTCAAGCCATCTCATGGCCACATGCCT GCTTTGGAGGCTGACTCGGAGGCACAACCGGCCTCAGGGCGTTCCTCAGGGACCCTACCT TTCTTGCTCCCTGAAGAAATGTGCACATTGCTTGAATAAAAACAATCAAAGAACACTCAG TCAAGATCGTCTGCTGCAGTCTTCGTTGAGGGCTGGGGATGCTAAAAGTCAGATGATTCA TGTGTACCCTGTCCATCCTAACTCACCTGCTCTTCTACTTCCGCAGCTTACTCCAGTGCC CACAGATACGACAGAGTGTCCCAAGTGCCCCTCACACTCTATTAGCTGCATCCTTAACCT CTTTTTGCCACACCATAAGCATTGGGTTTTGTTTGTTTTGAGATGGAGTCTTGCTCTGTT GCCAGGCTGGAGTGCAATGGCGTGATCTCAGCTCACTGCAATATCTGCGTCCAGGGTTCA AGCGATTCCCCTGCCTCAGCCTCCTGTATTAGCTGGGACTACAGGCGCACACCACCACGC GCAGCTAATTTTTTTGTATTTTAGTAGAGAAGGTTTCACGATGTTGGCCAGGATGGTCTC AATCTCCTGACCTCGTGATCTGCTCGCCTCGGCCTTCCAAAGTGCTGGGATTACAGGCAT GAGCCACGGCGCCTGGCCAGCATTGGGGTATTTTATTGAAGATGGAAGCCATGAATGTTG AGAAAGCCTCAGCAGATGGGAACTTGCCAGAGGTGATCTCTAACATCAAGGAGACTCTGA AGATAGTGTCCAGGACACCAGTTAACATCACTATGGCAGGGGACTCTGGCAATGGGATGT CCACCTTCATCAGTGCCCTTCGAAACACAGGACATGAGGGTAAGGCCTCACCTCCTACTG AGCTGGTAAAAGCTACCCAAAGATGTGCCTCCTATTTCTCTTCCCACTTTTCAAATGTGG TGTTGTGGGACCTGCCTGGCACAGGGTCTGCCACCACAACCCTGGAGAACTACCTGATGG AAATGCAGTTCAACCGGTATGACTTCATCATGGTTGCATCTGCACAATTCAGCATGAATC ATGTGATGCTTGCCAAAACCGCTGAGGACATGGGAAAGAAGTTCTACATTGTCTGGACCA AGCTAGACATGGACCTCAGCACAGGTGCCCTCCCAGAAGTGCAGCTACTGCAGATCAGAG AAAATGTCCTGGAAAATCTCCAGAAGGAGCGGGTATGTGAATACTAA OMIM ID 608212